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Stalled oligodendrocyte differentiation in IDH-mutant gliomas

BACKGROUND: Roughly 50% of adult gliomas harbor isocitrate dehydrogenase (IDH) mutations. According to the 2021 WHO classification guideline, these gliomas are diagnosed as astrocytomas, harboring no 1p19q co-deletion, or oligodendrogliomas, harboring 1p19q co-deletion. Recent studies report that ID...

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Detalles Bibliográficos
Autores principales: Wei, Yanfei, Li, Guanzhang, Feng, Jing, Wu, Fan, Zhao, Zheng, Bao, Zhaoshi, Zhang, Wei, Su, Xiaodong, Li, Jiuyi, Qi, Xueling, Duan, Zejun, Zhang, Yunqiu, Vega, Sandra Ferreyra, Jakola, Asgeir Store, Sun, Yingyu, Carén, Helena, Jiang, Tao, Fan, Xiaolong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10103394/
https://www.ncbi.nlm.nih.gov/pubmed/37055795
http://dx.doi.org/10.1186/s13073-023-01175-6