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The ability of Interleukin–10 to negate haemozoin-related pro-inflammatory effects has the potential to restore impaired macrophage function associated with malaria infection

BACKGROUND: Although pro-inflammatory cytokines are involved in the clearance of Plasmodium falciparum during the early stages of the infection, increased levels of these cytokines have been implicated in the pathogenesis of severe malaria. Amongst various parasite-derived inducers of inflammation,...

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Detalles Bibliográficos
Autores principales: Tembo, Dumizulu, Harawa, Visopo, Tran, Tam C., Afran, Louise, Molyneux, Malcolm E., Taylor, Terrie E., Seydel, Karl B., Nyirenda, Tonney, Russell, David G., Mandala, Wilson
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10103463/
https://www.ncbi.nlm.nih.gov/pubmed/37060041
http://dx.doi.org/10.1186/s12936-023-04539-w