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Association of APOE ε4/ε4 with fluid biomarkers in patients from the PUMCH dementia cohort

BACKGROUND: Apolipoprotein-E (APOE) ε4 is a major genetic risk factor for Alzheimer’s disease (AD). Current studies, which were mainly based on the clinical diagnosis rather than biomarkers, come to inconsistent conclusions regarding the associations of APOE ε4 homozygotes (APOE ε4/ε4) and cerebrosp...

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Detalles Bibliográficos
Autores principales: Shang, Li, Dong, Liling, Huang, Xinying, Wang, Tianyi, Mao, Chenhui, Li, Jie, Wang, Jie, Liu, Caiyan, Gao, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10103647/
https://www.ncbi.nlm.nih.gov/pubmed/37065463
http://dx.doi.org/10.3389/fnagi.2023.1119070