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Association of APOE ε4/ε4 with fluid biomarkers in patients from the PUMCH dementia cohort
BACKGROUND: Apolipoprotein-E (APOE) ε4 is a major genetic risk factor for Alzheimer’s disease (AD). Current studies, which were mainly based on the clinical diagnosis rather than biomarkers, come to inconsistent conclusions regarding the associations of APOE ε4 homozygotes (APOE ε4/ε4) and cerebrosp...
Autores principales: | Shang, Li, Dong, Liling, Huang, Xinying, Wang, Tianyi, Mao, Chenhui, Li, Jie, Wang, Jie, Liu, Caiyan, Gao, Jing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10103647/ https://www.ncbi.nlm.nih.gov/pubmed/37065463 http://dx.doi.org/10.3389/fnagi.2023.1119070 |
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