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PI(4,5)P(2) regulates the gating of Na(V)1.4 channels

Voltage-gated sodium (Na(V)) channels are densely expressed in most excitable cells and activate in response to depolarization, causing a rapid influx of Na(+) ions that initiates the action potential. The voltage-dependent activation of Na(V) channels is followed almost instantaneously by fast inac...

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Detalles Bibliográficos
Autores principales: Gada, Kirin D., Kamuene, Jordie M., Chandrashekar, Aishwarya, Kissell, R. Charles, Yauch, Anne K., Plant, Leigh D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10103707/
https://www.ncbi.nlm.nih.gov/pubmed/37043561
http://dx.doi.org/10.1085/jgp.202213255