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Induction of Innate Inflammatory Pathways in the Corneal Epithelium in the Desiccating Stress Dry Eye Model

PURPOSE: To determine whether 24-hour exposure to the desiccating stress (DS) dry eye model induces NF-kB and NLRP3 inflammasome pathways in the mouse cornea epithelium. METHODS: Six- to 8-week-old C57BL/6J mice were housed under normal humidity (nonstressed) or subjected to DS from a drafty, low-hu...

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Detalles Bibliográficos
Autores principales: Yu, Zhiyuan, Yazdanpanah, Ghasem, Alam, Jehan, de Paiva, Cintia S., Pflugfelder, Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10103726/
https://www.ncbi.nlm.nih.gov/pubmed/37036417
http://dx.doi.org/10.1167/iovs.64.4.8