BMP-4 and BMP-7 Inhibit EMT in a Model of Anterior Subcapsular Cataract in Part by Regulating the Notch Signaling Pathway

PURPOSE: The proliferation, migration, and epithelial-mesenchymal transition (EMT) of lens epithelial cells (LECs) are believed to be the pathological mechanisms underlying anterior subcapsular cataract (ASC). Bone morphogenetic proteins (BMPs) inhibit transforming growth factor-beta (TGF-β)-induced...

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Detalles Bibliográficos
Autores principales: Jiang, Fanying, Qin, Yingyan, Yang, Yuanfan, Li, Zhen, Cui, Baoyue, Ju, Rong, Wu, Mingxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2023
Materias:
Lens
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10103728/
https://www.ncbi.nlm.nih.gov/pubmed/37043340
http://dx.doi.org/10.1167/iovs.64.4.12

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10103728/
https://www.ncbi.nlm.nih.gov/pubmed/37043340
http://dx.doi.org/10.1167/iovs.64.4.12

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