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BMP-4 and BMP-7 Inhibit EMT in a Model of Anterior Subcapsular Cataract in Part by Regulating the Notch Signaling Pathway

PURPOSE: The proliferation, migration, and epithelial-mesenchymal transition (EMT) of lens epithelial cells (LECs) are believed to be the pathological mechanisms underlying anterior subcapsular cataract (ASC). Bone morphogenetic proteins (BMPs) inhibit transforming growth factor-beta (TGF-β)-induced...

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Detalles Bibliográficos
Autores principales:	Jiang, Fanying, Qin, Yingyan, Yang, Yuanfan, Li, Zhen, Cui, Baoyue, Ju, Rong, Wu, Mingxing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Association for Research in Vision and Ophthalmology 2023
Materias:	Lens
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10103728/ https://www.ncbi.nlm.nih.gov/pubmed/37043340 http://dx.doi.org/10.1167/iovs.64.4.12

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