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Dynamic molecular mechanism of the nuclear pore complex permeability barrier

Nuclear pore complexes (NPCs) mediate nucleocytoplasmic transport of specific macromolecules while impeding the exchange of unsolicited material. However, key aspects of this gating mechanism remain controversial. To address this issue, we determined the nanoscopic behavior of the permeability barri...

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Detalles Bibliográficos
Autores principales: Kozai, Toshiya, Fernandez-Martinez, Javier, van Eeuwen, Trevor, Gallardo, Paola, Kapinos, Larisa E., Mazur, Adam, Zhang, Wenzhu, Tempkin, Jeremy, Panatala, Radhakrishnan, Delgado-Izquierdo, Maria, Raveh, Barak, Sali, Andrej, Chait, Brian T., Veenhoff, Liesbeth M., Rout, Michael P., Lim, Roderick Y. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10103940/
https://www.ncbi.nlm.nih.gov/pubmed/37066338
http://dx.doi.org/10.1101/2023.03.31.535055