Cargando…

MRBEE: A novel bias-corrected multivariable Mendelian Randomization method

Mendelian randomization (MR) is an instrumental variable approach used to infer causal relationships between exposures and outcomes and can apply to summary data from genome-wide association studies (GWAS). Since GWAS summary statistics are subject to estimation errors, most existing MR approaches s...

Descripción completa

Detalles Bibliográficos
Autores principales: Lorincz-Comi, Noah, Yang, Yihe, Li, Gen, Zhu, Xiaofeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10103949/
https://www.ncbi.nlm.nih.gov/pubmed/37066391
http://dx.doi.org/10.1101/2023.01.10.523480