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Tamoxifen Response at Single Cell Resolution in Estrogen Receptor-Positive Primary Human Breast Tumors

In ER+/HER2- breast cancer, multiple measures of intra-tumor heterogeneity are associated with worse response to endocrine therapy. To investigate heterogeneity in response to treatment, we developed an operating room-to-laboratory pipeline for the collection of live human tumors and normal breast s...

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Detalles Bibliográficos
Autores principales: Kim, Hyunsoo, Whitman, Austin A., Wisniewska, Kamila, Kakati, Rasha T., Garcia-Recio, Susana, Calhoun, Benjamin C., Franco, Hector L., Perou, Charles M., Spanheimer, Philip M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10103953/
https://www.ncbi.nlm.nih.gov/pubmed/37066379
http://dx.doi.org/10.1101/2023.04.01.535159