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EGR1 regulates oral epithelial cell responses to Candida albicans via the EGFR- ERK1/2 pathway

Candida albicans is a fungal pathobiont colonising mucosal surfaces of the human body, including the oral cavity. Under certain predisposing conditions, C. albicans invades mucosal tissues activating EGFR-MAPK signalling pathways in epithelial cells via the action of its peptide toxin candidalysin....

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Detalles Bibliográficos
Autores principales: Dickenson, Ruth E., Pellon, Aize, Ponde, Nicole O., Hepworth, Olivia, Daniels Gatward, Lydia F., Naglik, Julian R., Moyes, David L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10103955/
https://www.ncbi.nlm.nih.gov/pubmed/37066428
http://dx.doi.org/10.1101/2023.03.31.535186