Cargando…

EGR1 regulates oral epithelial cell responses to Candida albicans via the EGFR- ERK1/2 pathway

Candida albicans is a fungal pathobiont colonising mucosal surfaces of the human body, including the oral cavity. Under certain predisposing conditions, C. albicans invades mucosal tissues activating EGFR-MAPK signalling pathways in epithelial cells via the action of its peptide toxin candidalysin....

Descripción completa

Detalles Bibliográficos
Autores principales:	Dickenson, Ruth E., Pellon, Aize, Ponde, Nicole O., Hepworth, Olivia, Daniels Gatward, Lydia F., Naglik, Julian R., Moyes, David L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10103955/ https://www.ncbi.nlm.nih.gov/pubmed/37066428 http://dx.doi.org/10.1101/2023.03.31.535186

Ejemplares similares

Receptor-kinase EGFR-MAPK adaptor proteins mediate the epithelial response to Candida albicans via the cytolytic peptide toxin, candidalysin
por: Ponde, Nicole O., et al.
Publicado: (2022)

Mucosal Immunity and Candida albicans Infection
por: Moyes, David L., et al.
Publicado: (2011)

New Insights in Candida albicans Innate Immunity at the Mucosa: Toxins, Epithelium, Metabolism, and Beyond
por: Pellon, Aize, et al.
Publicado: (2020)

Candida albicans Pathogenicity and Epithelial Immunity
por: Naglik, Julian R., et al.
Publicado: (2014)

The Candida albicans toxin candidalysin mediates distinct epithelial inflammatory responses through p38 and EGFR-ERK pathways
por: Nikou, Spyridoula-Angeliki, et al.
Publicado: (2022)

Candida albicans-epithelial interactions and pathogenicity mechanisms: scratching the surface
por: Moyes, David L, et al.
Publicado: (2015)

Candida albicans Interactions with Mucosal Surfaces during Health and Disease
por: Nikou, Spyridoula-Angeliki, et al.
Publicado: (2019)

Candida albicans Yeast and Hyphae are Discriminated by MAPK Signaling in Vaginal Epithelial Cells
por: Moyes, David L., et al.
Publicado: (2011)

Candidalysin: discovery and function in Candida albicans infections
por: Naglik, Julian R, et al.
Publicado: (2019)

Processing of Candida albicans Ece1p Is Critical for Candidalysin Maturation and Fungal Virulence
por: Richardson, Jonathan P., et al.
Publicado: (2018)

Albumin Neutralizes Hydrophobic Toxins and Modulates Candida albicans Pathogenicity
por: Austermeier, Sophie, et al.
Publicado: (2021)

Evaluation of the Role of Candida albicans Agglutinin-Like Sequence (Als) Proteins in Human Oral Epithelial Cell Interactions
por: Murciano, Celia, et al.
Publicado: (2012)

Role of Cellular Metabolism during Candida-Host Interactions
por: Pellon, Aize, et al.
Publicado: (2022)

Candida albicans and candidalysin in inflammatory disorders and cancer
por: Ho, Jemima, et al.
Publicado: (2020)

Candidalysin Is Required for Neutrophil Recruitment and Virulence During Systemic Candida albicans Infection
por: Swidergall, Marc, et al.
Publicado: (2019)

The Missing Link between Candida albicans Hyphal Morphogenesis and Host Cell Damage
por: Wilson, Duncan, et al.
Publicado: (2016)

The Host Cell Transcription Factor EGR1 Is Induced by Bacteria through the EGFR–ERK1/2 Pathway
por: de Klerk, Nele, et al.
Publicado: (2017)

Protection Against Epithelial Damage During Candida albicans Infection Is Mediated by PI3K/Akt and Mammalian Target of Rapamycin Signaling
por: Moyes, David L., et al.
Publicado: (2014)

Candida albicans Increases Tumor Cell Adhesion to Endothelial Cells In Vitro: Intraspecific Differences and Importance of the Mannose Receptor
por: Ramirez-Garcia, Andoni, et al.
Publicado: (2013)

Adaptive immune responses to Candida albicans infection
por: Richardson, Jonathan P, et al.
Publicado: (2015)

A Biphasic Innate Immune MAPK Response Discriminates between the Yeast and Hyphal Forms of Candida albicans in Epithelial Cells
por: Moyes, David L., et al.
Publicado: (2010)

Genome Sequence for Candida albicans Clinical Oral Isolate 529L
por: Cuomo, Christina A., et al.
Publicado: (2019)

Integrative functional analysis uncovers metabolic differences between Candida species
por: Begum, Neelu, et al.
Publicado: (2022)

The monoclonal antibody Ca37, developed against Candida albicans alcohol dehydrogenase, inhibits the yeast in vitro and in vivo
por: Antoran, Aitziber, et al.
Publicado: (2020)

Mixed Candida albicans strain populations in colonized and infected mucosal tissues
por: Jacobsen, Mette D, et al.
Publicado: (2008)

Candida albicans Enhances the Progression of Oral Squamous Cell Carcinoma In Vitro and In Vivo
por: Vadovics, Máté, et al.
Publicado: (2022)

Candida albicans-Induced Epithelial Damage Mediates Translocation through Intestinal Barriers
por: Allert, Stefanie, et al.
Publicado: (2018)

Gfi1-Mediated Repression of c-Fos, Egr-1 and Egr-2, and Inhibition of ERK1/2 Signaling Contribute to the Role of Gfi1 in Granulopoiesis
por: Zhang, Yangyang, et al.
Publicado: (2019)

Cell Cycle-Independent Phospho-Regulation of Fkh2 during Hyphal Growth Regulates Candida albicans Pathogenesis
por: Greig, Jamie A., et al.
Publicado: (2015)

Calcium-dependent ESCRT recruitment and lysosome exocytosis maintain epithelial integrity during Candida albicans invasion
por: Westman, Johannes, et al.
Publicado: (2022)

Candida albicans induces neutrophil extracellular traps and leucotoxic hypercitrullination via candidalysin
por: Unger, Lucas, et al.
Publicado: (2023)

A variant ECE1 allele contributes to reduced pathogenicity of Candida albicans during vulvovaginal candidiasis
por: Liu, Junyan, et al.
Publicado: (2021)

Candida–Epithelial Interactions
por: Richardson, Jonathan P., et al.
Publicado: (2018)

Multi-species biofilm of Candida albicans and non-Candida albicans Candida species on acrylic substrate
por: K PATHAK, Apurva, et al.
Publicado: (2012)

EFG1 Mutations, Phenotypic Switching, and Colonization by Clinical a/α Strains of Candida albicans
por: Park, Yang-Nim, et al.
Publicado: (2020)

The EGFR family members sustain the neoplastic phenotype of ALK+ lung adenocarcinoma via EGR1
por: Voena, C, et al.
Publicado: (2013)

Candida albicans versus Candida dubliniensis: Why Is C. albicans More Pathogenic?
por: Moran, Gary P., et al.
Publicado: (2012)

Azole Antifungal Resistance in Candida albicans and Emerging Non-albicans Candida Species
por: Whaley, Sarah G., et al.
Publicado: (2017)

Biofilm Matrix Regulation by Candida albicans Zap1
por: Nobile, Clarissa J., et al.
Publicado: (2009)

Candida albicans Delays HIV-1 Replication in Macrophages
por: Rodriguez Rodrigues, Christian, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_l07v6m9jlqk2ag30l6d7enang9