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Peptidoglycan from Bacillus anthracis Inhibits Human Macrophage Efferocytosis in Part by Reducing Cell Surface Expression of MERTK and TIM-3

Bacillus anthracis peptidoglycan (PGN) is a major component of the bacterial cell wall and a key pathogen-associated molecular pattern (PAMP) contributing to anthrax pathology, including organ dysfunction and coagulopathy. Increases in apoptotic lymphocytes are a late-stage feature of anthrax and se...

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Detalles Bibliográficos
Autores principales: Mytych, Joshua S, Pan, Zijian, Lopez-Davis, Charmaine, Redinger, Nancy, Lawrence, Christina, Ziegler, Jadith, Popescu, Narcis I., James, Judith A., Farris, A. Darise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10103956/
https://www.ncbi.nlm.nih.gov/pubmed/37066181
http://dx.doi.org/10.1101/2023.03.30.535001