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ITK signaling regulates a switch between T helper 17 and T regulatory cell lineages via a calcium-mediated pathway
The balance of pro-inflammatory T helper type 17 (Th17) and anti-inflammatory T regulatory (Treg) cells is crucial in maintaining immune homeostasis in health and disease conditions. Differentiation of naïve CD4(+) T cells into Th17/Treg cells is dependent upon T cell receptor (TCR) activation and c...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10103963/ https://www.ncbi.nlm.nih.gov/pubmed/37066370 http://dx.doi.org/10.1101/2023.04.01.535229 |