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ITK signaling regulates a switch between T helper 17 and T regulatory cell lineages via a calcium-mediated pathway

The balance of pro-inflammatory T helper type 17 (Th17) and anti-inflammatory T regulatory (Treg) cells is crucial in maintaining immune homeostasis in health and disease conditions. Differentiation of naïve CD4(+) T cells into Th17/Treg cells is dependent upon T cell receptor (TCR) activation and c...

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Detalles Bibliográficos
Autores principales:	Anannya, Orchi, Huang, Weishan, August, Avery
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10103963/ https://www.ncbi.nlm.nih.gov/pubmed/37066370 http://dx.doi.org/10.1101/2023.04.01.535229

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