Systemic Proteome Phenotypes Reveal Defective Metabolic Flexibility in Mecp2 Mutants

Genes mutated in monogenic neurodevelopmental disorders are broadly expressed. This observation supports the concept that monogenic neurodevelopmental disorders are systemic diseases that profoundly impact neurodevelopment. We tested the systemic disease model focusing on Rett syndrome, which is cau...

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Detalles Bibliográficos
Autores principales: Zlatic, Stephanie A., Werner, Erica, Surapaneni, Veda, Lee, Chelsea E., Gokhale, Avanti, Singleton, Kaela, Duong, Duc, Crocker, Amanda, Gentile, Karen, Middleton, Frank, Dalloul, Joseph Martin, Liu, William Li-Yun, Patgiri, Anupam, Tarquinio, Daniel, Carpenter, Randall, Faundez, Victor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10103972/
https://www.ncbi.nlm.nih.gov/pubmed/37066332
http://dx.doi.org/10.1101/2023.04.03.535431

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10103972/
https://www.ncbi.nlm.nih.gov/pubmed/37066332
http://dx.doi.org/10.1101/2023.04.03.535431

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