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High-throughput colocalization pipeline quantifies efficacy of mitochondrial targeting signals across different protein types
Efficient metabolic engineering and the development of mitochondrial therapeutics often rely upon the specific and strong import of foreign proteins into mitochondria. Fusing a protein to a mitochondria-bound signal peptide is a common method to localize proteins to mitochondria, but this strategy i...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10103990/ https://www.ncbi.nlm.nih.gov/pubmed/37066162 http://dx.doi.org/10.1101/2023.04.03.535288 |