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A hybrid single cell demultiplexing strategy that increases both cell recovery rate and calling accuracy

Recent advances in single cell RNA sequencing allow users to pool multiple samples into one run and demultiplex in downstream analysis, greatly increasing the experimental efficiency and cost-effectiveness. However, the expensive reagents for cell labeling, limited pooling capacity, non-ideal cell r...

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Detalles Bibliográficos
Autores principales: Li, Lei, Sun, Jiayi, Fu, Yanbin, Changrob, Siriruk, McGrath, Joshua J.C., Wilson, Patrick C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104010/
https://www.ncbi.nlm.nih.gov/pubmed/37066221
http://dx.doi.org/10.1101/2023.04.02.535299