Histone Deacetylases (HDACs) maintain expression of the pluripotent gene network via recruitment of RNA polymerase II to coding and non-coding loci

Histone acetylation is a dynamic modification regulated by the opposing actions of histone acetyltransferases (HATs) and histone deacetylases (HDACs). Deacetylation of histone tails results in chromatin tightening and therefore HDACs are generally regarded as transcriptional repressors. Counterintui...

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Detalles Bibliográficos
Autores principales: RDW, Kelly, KR, Stengel, A, Chandru, LC4, Johnson, SW, Hiebert, SM, Cowley
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104071/
https://www.ncbi.nlm.nih.gov/pubmed/37066171
http://dx.doi.org/10.1101/2023.04.06.535398

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104071/
https://www.ncbi.nlm.nih.gov/pubmed/37066171
http://dx.doi.org/10.1101/2023.04.06.535398

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