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Both CD8 and CD4 T cells contribute to immunosurveillance preventing the development of neoantigen-expressing autochthonous sarcomas

The adaptive immune system plays an essential anti-tumor role through immunosurveillance and response to immunotherapies. Characterizing phenotypic features and mechanisms of dysfunction of tumor-specific T cell populations may uncover novel immunotherapeutic targets and biomarkers of response. To s...

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Detalles Bibliográficos
Autores principales: Himes, Jonathon E., Wisdom, Amy J., Wang, Laura, Shepard, Sam J., Daniel, Andrea R., Williams, Nerissa, Luo, Lixia, Ma, Yan, Mowery, Yvonne M., Kirsch, David G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104072/
https://www.ncbi.nlm.nih.gov/pubmed/37066384
http://dx.doi.org/10.1101/2023.04.04.535550