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Increased response to immune checkpoint inhibitors with dietary methionine restriction

Dietary methionine restriction, defined as reduction of methionine intake by around 80%, reproducibly decreases tumor growth and synergizes with cancer therapies. Here, we combined dietary methionine restriction with immune checkpoint inhibitors in a model of colon adenocarcinoma. In vitro, we obser...

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Detalles Bibliográficos
Autores principales: Morehead, Lauren C., Garg, Sarita, Wallis, Katherine F., Siegel, Eric R., Tackett, Alan J., Miousse, Isabelle R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104076/
https://www.ncbi.nlm.nih.gov/pubmed/37066240
http://dx.doi.org/10.1101/2023.04.05.535695