Untangling the mechanisms of pulmonary hypertension-induced right ventricular stiffening in a large animal model

BACKGROUND: Pulmonary arterial hypertension (PHT) is a devastating disease with low survival rates. In PHT, chronic pressure overload leads to right ventricle (RV) remodeling and stiffening; thus, impeding diastolic filling and ventricular function. Multiple mechanisms contribute to RV stiffening, i...

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Detalles Bibliográficos
Autores principales: Kakaletsis, Sotirios, Malinowski, Marcin, Mathur, Mrudang, Sugerman, Gabriella P., Lucy, Jeff J., Snider, Caleb, Jazwiec, Tomasz, Bersi, Matthew, Timek, Tomasz A., Rausch, Manuel K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104078/
https://www.ncbi.nlm.nih.gov/pubmed/37066294
http://dx.doi.org/10.1101/2023.04.03.535491

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104078/
https://www.ncbi.nlm.nih.gov/pubmed/37066294
http://dx.doi.org/10.1101/2023.04.03.535491

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