Pancreatic loss of Mig6 alters murine endocrine cell fate and protects functional beta cell mass in an STZ-induced model of diabetes

BACKGROUND: Maintaining functional beta cell mass (BCM) to meet glycemic demands is essential to preventing or reversing the progression of diabetes. Yet the mechanisms that establish and regulate endocrine cell fate are incompletely understood. We sought to determine the impact of deletion of mitog...

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Detalles Bibliográficos
Autores principales: Bauer, Brandon M., Irimia, Jose M., Bloom-Saldana, Elizabeth, Jeong, Jae-Wook, Fueger, Patrick T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104126/
https://www.ncbi.nlm.nih.gov/pubmed/37066257
http://dx.doi.org/10.1101/2023.04.07.536046

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104126/
https://www.ncbi.nlm.nih.gov/pubmed/37066257
http://dx.doi.org/10.1101/2023.04.07.536046

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