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Stepwise design of pseudosymmetric protein hetero-oligomers

Pseudosymmetric hetero-oligomers with three or more unique subunits with overall structural (but not sequence) symmetry play key roles in biology, and systematic approaches for generating such proteins de novo would provide new routes to controlling cell signaling and designing complex protein mater...

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Detalles Bibliográficos
Autores principales: Kibler, Ryan D., Lee, Sangmin, Kennedy, Madison A., Wicky, Basile I. M., Lai, Stella M., Kostelic, Marius M., Li, Xinting, Chow, Cameron M., Carter, Lauren, Wysocki, Vicki H., Stoddard, Barry L., Baker, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104133/
https://www.ncbi.nlm.nih.gov/pubmed/37066191
http://dx.doi.org/10.1101/2023.04.07.535760