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Stepwise design of pseudosymmetric protein hetero-oligomers
Pseudosymmetric hetero-oligomers with three or more unique subunits with overall structural (but not sequence) symmetry play key roles in biology, and systematic approaches for generating such proteins de novo would provide new routes to controlling cell signaling and designing complex protein mater...
Autores principales: | Kibler, Ryan D., Lee, Sangmin, Kennedy, Madison A., Wicky, Basile I. M., Lai, Stella M., Kostelic, Marius M., Li, Xinting, Chow, Cameron M., Carter, Lauren, Wysocki, Vicki H., Stoddard, Barry L., Baker, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104133/ https://www.ncbi.nlm.nih.gov/pubmed/37066191 http://dx.doi.org/10.1101/2023.04.07.535760 |
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