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The Chromatin Landscape of Pathogenic Transcriptional Cell States in Rheumatoid Arthritis

Synovial tissue inflammation is the hallmark of rheumatoid arthritis (RA). Recent work has identified prominent pathogenic cell states in inflamed RA synovial tissue, such as T peripheral helper cells; however, the epigenetic regulation of these states has yet to be defined. We measured genome-wide...

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Detalles Bibliográficos
Autores principales: Weinand, Kathryn, Sakaue, Saori, Nathan, Aparna, Jonsson, Anna Helena, Zhang, Fan, Watts, Gerald F. M., Zhu, Zhu, Rao, Deepak A., Anolik, Jennifer H., Brenner, Michael B., Donlin, Laura T., Wei, Kevin, Raychaudhuri, Soumya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104143/
https://www.ncbi.nlm.nih.gov/pubmed/37066336
http://dx.doi.org/10.1101/2023.04.07.536026