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Alzheimer’s disease-specific cytokine secretion suppresses neuronal mitochondrial metabolism

INTRODUCTION: Neuroinflammation and metabolic dysfunction are early alterations in Alzheimer’s disease brain that are thought to contribute to disease onset and progression. Glial activation due to protein deposition results in cytokine secretion and shifts in brain metabolism, which have been obser...

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Detalles Bibliográficos
Autores principales: Kuhn, Madison K., Fleeman, Rebecca M., Beidler, Lynne M., Snyder, Amanda M., Chan, Dennis C., Proctor, Elizabeth A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104145/
https://www.ncbi.nlm.nih.gov/pubmed/37066287
http://dx.doi.org/10.1101/2023.04.07.536014