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Late gene therapy limits the restoration of retinal function in a mouse model of retinitis pigmentosa
Retinitis pigmentosa is an inherited photoreceptor degeneration that begins with rod loss followed by cone loss and eventual blindness. Gene therapies are being developed, but it is unknown how retinal function depends on the time of intervention. To uncover this dependence, we utilized a mouse mode...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104154/ https://www.ncbi.nlm.nih.gov/pubmed/37066264 http://dx.doi.org/10.1101/2023.04.07.536035 |