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Neural substrates of cognitive impairment in a NMDAR hypofunction mouse model of schizophrenia and partial rescue by risperidone

N-methyl D-aspartate receptor (NMDAR) hypofunction is a pathophysiological mechanism relevant for schizophrenia. Acute administration of the NMDAR antagonist phencyclidine (PCP) induces psychosis in patients and animals while subchronic PCP (sPCP) produces cognitive dysfunction for weeks. We investi...

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Detalles Bibliográficos
Autores principales: Delgado-Sallent, Cristina, Gener, Thomas, Nebot, Pau, López-Cabezón, Cristina, Puig, M. Victoria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104169/
https://www.ncbi.nlm.nih.gov/pubmed/37066076
http://dx.doi.org/10.3389/fncel.2023.1152248