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High-Dimensional Mediation Analysis: A New Method Applied to Maternal Smoking, Placental DNA Methylation, and Birth Outcomes

BACKGROUND: High-dimensional mediation analysis is an extension of unidimensional mediation analysis that includes multiple mediators, and increasingly it is being used to evaluate the indirect omics-layer effects of environmental exposures on health outcomes. Analyses involving high-dimensional med...

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Detalles Bibliográficos
Autores principales: Jumentier, Basile, Barrot, Claire-Cécile, Estavoyer, Maxime, Tost, Jorg, Heude, Barbara, François, Olivier, Lepeule, Johanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Environmental Health Perspectives 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104171/
https://www.ncbi.nlm.nih.gov/pubmed/37058433
http://dx.doi.org/10.1289/EHP11559