Evolutionary druggability: leveraging low-dimensional fitness landscapes towards new metrics for antimicrobial applications

The term “druggability” describes the molecular properties of drugs or targets in pharmacological interventions and is commonly used in work involving drug development for clinical applications. There are no current analogues for this notion that quantify the drug-target interaction with respect to...

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Detalles Bibliográficos
Autores principales: Guerrero, Rafael F., Dorji, Tandin, Harris, Ra’Mal M., Shoulders, Matthew D., Ogbunugafor, C. Brandon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104179/
https://www.ncbi.nlm.nih.gov/pubmed/37066376
http://dx.doi.org/10.1101/2023.04.08.536116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104179/
https://www.ncbi.nlm.nih.gov/pubmed/37066376
http://dx.doi.org/10.1101/2023.04.08.536116

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