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Evolutionary druggability: leveraging low-dimensional fitness landscapes towards new metrics for antimicrobial applications
The term “druggability” describes the molecular properties of drugs or targets in pharmacological interventions and is commonly used in work involving drug development for clinical applications. There are no current analogues for this notion that quantify the drug-target interaction with respect to...
Autores principales: | Guerrero, Rafael F., Dorji, Tandin, Harris, Ra’Mal M., Shoulders, Matthew D., Ogbunugafor, C. Brandon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104179/ https://www.ncbi.nlm.nih.gov/pubmed/37066376 http://dx.doi.org/10.1101/2023.04.08.536116 |
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