Multiomic approach and Mendelian randomization analysis identify causal associations between blood biomarkers and subcortical brain structure volumes

Alterations in subcortical brain structure volumes have been found to be associated with several neurodegenerative and psychiatric disorders. At the same time, genome-wide association studies (GWAS) have identified numerous common variants associated with brain structure. In this study, we integrate...

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Detalles Bibliográficos
Autores principales: Jain, Pritesh, Yates, Madison, de Celis, Carlos Rubin, Drineas, Petros, Jahanshad, Neda, Thompson, Paul, Paschou, Peristera
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104218/
https://www.ncbi.nlm.nih.gov/pubmed/37066330
http://dx.doi.org/10.1101/2023.03.30.23287968

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104218/
https://www.ncbi.nlm.nih.gov/pubmed/37066330
http://dx.doi.org/10.1101/2023.03.30.23287968

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