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Fine particulate air pollution and neuropathology markers of Alzheimer’s disease in donors with and without APOE ε4 alleles – results from an autopsy cohort

INTRODUCTION: Higher fine particulate matter (PM(2.5)) exposure has been found to be associated with Alzheimer’s disease (AD). PM(2.5) has been hypothesized to cause inflammation and oxidative stress in the brain, contributing to neuropathology. A major genetic risk factor of AD, the apolipoprotein...

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Detalles Bibliográficos
Autores principales: Christensen, Grace M., Li, Zhenjiang, Liang, Donghai, Ebelt, Stefanie, Gearing, Marla, Levey, Allan I., Lah, James J., Wingo, Aliza P., Wingo, Thomas S., Huels, Anke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104229/
https://www.ncbi.nlm.nih.gov/pubmed/37066193
http://dx.doi.org/10.1101/2023.04.07.23288288