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Assessment of morning sleep propensity with lemborexant in adults with insomnia disorder in a randomized, placebo-controlled crossover study

OBJECTIVE: To evaluate effects of lemborexant (LEM), a dual orexin receptor antagonist, on next-morning sleep propensity assessed by a modified Multiple Sleep Latency Test (M-MSLT) in adults with insomnia disorder. METHODS: Study 107 (E2006-A001-107) was a phase 1, randomized, double-blind, four-per...

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Detalles Bibliográficos
Autores principales: Mayleben, David, Rosenberg, Russell, Pinner, Kate, Hussein, Ziad, Moline, Margaret
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104417/
https://www.ncbi.nlm.nih.gov/pubmed/37193566
http://dx.doi.org/10.1093/sleepadvances/zpab011