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Mammals sustain amino acid homochirality against chiral conversion by symbiotic microbes

Mammals exhibit systemic homochirality of amino acids in L-configurations. While ribosomal protein synthesis requires rigorous chiral selection for L-amino acids, both endogenous and microbial enzymes convert diverse L-amino acids to D-configurations in mammals. However, it is not clear how mammals...

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Detalles Bibliográficos
Autores principales: Gonda, Yusuke, Matsuda, Akina, Adachi, Kenichiro, Ishii, Chiharu, Suzuki, Masataka, Osaki, Akina, Mita, Masashi, Nishizaki, Naoto, Ohtomo, Yoshiyuki, Shimizu, Toshiaki, Yasui, Masato, Hamase, Kenji, Sasabe, Jumpei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104486/
https://www.ncbi.nlm.nih.gov/pubmed/37014864
http://dx.doi.org/10.1073/pnas.2300817120