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Infection of primary nasal epithelial cells differentiates among lethal and seasonal human coronaviruses

The nasal epithelium is the initial entry portal and primary barrier to infection by all human coronaviruses (HCoVs). We utilize primary human nasal epithelial cells grown at air–liquid interface, which recapitulate the heterogeneous cellular population as well as mucociliary clearance functions of...

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Detalles Bibliográficos
Autores principales: Otter, Clayton J., Fausto, Alejandra, Tan, Li Hui, Khosla, Alisha S., Cohen, Noam A., Weiss, Susan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104492/
https://www.ncbi.nlm.nih.gov/pubmed/37023127
http://dx.doi.org/10.1073/pnas.2218083120