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FOXO-mediated repression of Dicer1 regulates metabolism, stress resistance, and longevity in Drosophila
The adipose tissue plays a crucial role in metabolism and physiology, affecting animal lifespan and susceptibility to disease. In this study, we present evidence that adipose Dicer1 (Dcr-1), a conserved type III endoribonuclease involved in miRNA processing, plays a crucial role in the regulation of...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104520/ https://www.ncbi.nlm.nih.gov/pubmed/37014862 http://dx.doi.org/10.1073/pnas.2216539120 |