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FOXO-mediated repression of Dicer1 regulates metabolism, stress resistance, and longevity in Drosophila

The adipose tissue plays a crucial role in metabolism and physiology, affecting animal lifespan and susceptibility to disease. In this study, we present evidence that adipose Dicer1 (Dcr-1), a conserved type III endoribonuclease involved in miRNA processing, plays a crucial role in the regulation of...

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Detalles Bibliográficos
Autores principales: Sánchez, Juan A., Ingaramo, María C., Gervé, María P., Thomas, Maria G., Boccaccio, Graciela L., Dekanty, Andrés
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104520/
https://www.ncbi.nlm.nih.gov/pubmed/37014862
http://dx.doi.org/10.1073/pnas.2216539120