Spectra and characteristics of somatic mutations induced by ionizing radiation in hematopoietic stem cells

Spectra and frequencies of spontaneous and X-ray-induced somatic mutations were revealed with mouse long-term hematopoietic stem cells (LT-HSCs) by whole-genome sequencing of clonal cell populations propagated in vitro from single isolated LT-HSCs. SNVs and small indels were the most common types of...

Descripción completa

Detalles Bibliográficos
Autores principales: Matsuda, Yukiko, Uchimura, Arikuni, Satoh, Yasunari, Kato, Naohiro, Toshishige, Masaaki, Kajimura, Junko, Hamasaki, Kanya, Yoshida, Kengo, Hayashi, Tomonori, Noda, Asao, Tanabe, Osamu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104525/
https://www.ncbi.nlm.nih.gov/pubmed/37018193
http://dx.doi.org/10.1073/pnas.2216550120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104525/
https://www.ncbi.nlm.nih.gov/pubmed/37018193
http://dx.doi.org/10.1073/pnas.2216550120

Ejemplares similares