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Spectra and characteristics of somatic mutations induced by ionizing radiation in hematopoietic stem cells

Spectra and frequencies of spontaneous and X-ray-induced somatic mutations were revealed with mouse long-term hematopoietic stem cells (LT-HSCs) by whole-genome sequencing of clonal cell populations propagated in vitro from single isolated LT-HSCs. SNVs and small indels were the most common types of...

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Detalles Bibliográficos
Autores principales:	Matsuda, Yukiko, Uchimura, Arikuni, Satoh, Yasunari, Kato, Naohiro, Toshishige, Masaaki, Kajimura, Junko, Hamasaki, Kanya, Yoshida, Kengo, Hayashi, Tomonori, Noda, Asao, Tanabe, Osamu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2023
Materias:	Biological Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104525/ https://www.ncbi.nlm.nih.gov/pubmed/37018193 http://dx.doi.org/10.1073/pnas.2216550120

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