eIF2Bδ blocks the integrated stress response and maintains eIF2B activity and cancer metastasis by overexpression in breast cancer stem cells

Breast cancer (BC) metastasis involves cancer stem cells (CSCs) and their regulation by micro-RNAs (miRs), but miR targeting of the translation machinery in CSCs is poorly explored. We therefore screened miR expression levels in a range of BC cell lines, comparing non-CSCs to CSCs, and focused on mi...

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Detalles Bibliográficos
Autores principales: Gupta, Malavika, Walters, Beth A., Katsara, Olga, Granados Blanco, Karol, Geter, Phillip A., Schneider, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104532/
https://www.ncbi.nlm.nih.gov/pubmed/37014850
http://dx.doi.org/10.1073/pnas.2207898120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104532/
https://www.ncbi.nlm.nih.gov/pubmed/37014850
http://dx.doi.org/10.1073/pnas.2207898120

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