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eIF2Bδ blocks the integrated stress response and maintains eIF2B activity and cancer metastasis by overexpression in breast cancer stem cells
Breast cancer (BC) metastasis involves cancer stem cells (CSCs) and their regulation by micro-RNAs (miRs), but miR targeting of the translation machinery in CSCs is poorly explored. We therefore screened miR expression levels in a range of BC cell lines, comparing non-CSCs to CSCs, and focused on mi...
Autores principales: | Gupta, Malavika, Walters, Beth A., Katsara, Olga, Granados Blanco, Karol, Geter, Phillip A., Schneider, Robert J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104532/ https://www.ncbi.nlm.nih.gov/pubmed/37014850 http://dx.doi.org/10.1073/pnas.2207898120 |
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