Cargando…
Deciphering the evolution of flavin-dependent monooxygenase stereoselectivity using ancestral sequence reconstruction
Controlling the selectivity of a reaction is critical for target-oriented synthesis. Accessing complementary selectivity profiles enables divergent synthetic strategies, but is challenging to achieve in biocatalytic reactions given enzymes’ innate preferences of a single selectivity. Thus, it is cri...
| Autores principales: | , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2023
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104550/ https://www.ncbi.nlm.nih.gov/pubmed/37014851 http://dx.doi.org/10.1073/pnas.2218248120 |