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Subclass-switched anti-spike IgG3 oligoclonal cocktails strongly enhance Fc-mediated opsonization

Antibodies play a central role in the immune defense against SARS-CoV-2. Emerging evidence has shown that nonneutralizing antibodies are important for immune defense through Fc-mediated effector functions. Antibody subclass is known to affect downstream Fc function. However, whether the antibody sub...

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Detalles Bibliográficos
Autores principales: Izadi, Arman, Hailu, Arsema, Godzwon, Magdalena, Wrighton, Sebastian, Olofsson, Berit, Schmidt, Tobias, Söderlund-Strand, Anna, Elder, Elizabeth, Appelberg, Sofia, Valsjö, Maria, Larsson, Olivia, Wendel-Hansen, Vidar, Ohlin, Mats, Bahnan, Wael, Nordenfelt, Pontus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104557/
https://www.ncbi.nlm.nih.gov/pubmed/37011197
http://dx.doi.org/10.1073/pnas.2217590120