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Subclass-switched anti-spike IgG3 oligoclonal cocktails strongly enhance Fc-mediated opsonization
Antibodies play a central role in the immune defense against SARS-CoV-2. Emerging evidence has shown that nonneutralizing antibodies are important for immune defense through Fc-mediated effector functions. Antibody subclass is known to affect downstream Fc function. However, whether the antibody sub...
Autores principales: | Izadi, Arman, Hailu, Arsema, Godzwon, Magdalena, Wrighton, Sebastian, Olofsson, Berit, Schmidt, Tobias, Söderlund-Strand, Anna, Elder, Elizabeth, Appelberg, Sofia, Valsjö, Maria, Larsson, Olivia, Wendel-Hansen, Vidar, Ohlin, Mats, Bahnan, Wael, Nordenfelt, Pontus |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104557/ https://www.ncbi.nlm.nih.gov/pubmed/37011197 http://dx.doi.org/10.1073/pnas.2217590120 |
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