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Accessory cells precondition naïve T cells and regulatory T cells for cytokine-mediated proliferation

Naïve T cells and regulatory T cells, when purified, do not proliferate to the γ(c)-cytokines IL-2, IL-7, or IL-15, despite their expression of cognate cytokine receptors. Dendritic cells (DCs) enabled the T cell proliferation to these cytokines, through cell-to-cell contact, but independent of T ce...

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Detalles Bibliográficos
Autores principales: Sato, Noriko, Bamford, Richard N., Bryant, Bonita R., Tagaya, Yutaka, Waldmann, Thomas A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104559/
https://www.ncbi.nlm.nih.gov/pubmed/37014858
http://dx.doi.org/10.1073/pnas.2217562120