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A fitness trade-off explains the early fate of yeast aneuploids with chromosome gains

The early development of aneuploidy from an accidental chromosome missegregation shows contrasting effects. On the one hand, it is associated with significant cellular stress and decreased fitness. On the other hand, it often carries a beneficial effect and provides a quick (but typically transient)...

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Detalles Bibliográficos
Autores principales: Pompei, Simone, Cosentino Lagomarsino, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104565/
https://www.ncbi.nlm.nih.gov/pubmed/37018197
http://dx.doi.org/10.1073/pnas.2211687120