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A fitness trade-off explains the early fate of yeast aneuploids with chromosome gains
The early development of aneuploidy from an accidental chromosome missegregation shows contrasting effects. On the one hand, it is associated with significant cellular stress and decreased fitness. On the other hand, it often carries a beneficial effect and provides a quick (but typically transient)...
Autores principales: | Pompei, Simone, Cosentino Lagomarsino, Marco |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104565/ https://www.ncbi.nlm.nih.gov/pubmed/37018197 http://dx.doi.org/10.1073/pnas.2211687120 |
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