Shigella IpaH9.8 limits GBP1-dependent LPS release from intracytosolic bacteria to suppress caspase-4 activation

Pyroptosis is an inflammatory form of cell death induced upon recognition of invading microbes. During an infection, pyroptosis is enhanced in interferon-gamma-exposed cells via the actions of members of the guanylate-binding protein (GBP) family. GBPs promote caspase-4 (CASP4) activation by enhanci...

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Detalles Bibliográficos
Autores principales: Goers, Lisa, Kim, Kyungsub, Stedman, Teagan C., Canning, Patrick J., Mou, Xiangyu, Ernst, Nadja Heinz, Coers, Jörn, Lesser, Cammie F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104580/
https://www.ncbi.nlm.nih.gov/pubmed/37014865
http://dx.doi.org/10.1073/pnas.2218469120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104580/
https://www.ncbi.nlm.nih.gov/pubmed/37014865
http://dx.doi.org/10.1073/pnas.2218469120

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